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The purpose of this study is to assess whether the use of local anesthetic to numb the nerves that run deeper in the abdominal wall gives better post operative pain control than just infiltrating local anesthetic to the wound edges.
Local anesthetic is often administered during an operation to reduce post operative wound pain. Whilst this is frequently done during an appendectomy there is currently no evidence to suggest whether there is any benefit to the patient to injecting the local anesthetic deeper to block the nerves supplying abdominal wall sensation, compared to using it just in the skin around the wound.
Comparison: Post operative pain scores following appendectomy for patients given skin infiltration of local anesthetic (pre incision), compared to patients given both preincision wound infiltration and deeper field infiltration with local anesthetic(deep to external oblique).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A | Active Comparator | lanz incision appendectomy |
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| B | Active Comparator | lanz incision appendectomy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| local anesthetic administration | Procedure | Pre incision skin infiltration with local anesthetic 0.5% bupivacaine by weight OR Pre incision skin infiltration and deeper field infiltration (deep to external oblique) with local anesthetic 0.5% bupivavcaine by weight |
| Measure | Description | Time Frame |
|---|---|---|
| Post operative pain score | 1 hour, 4 hours, 8 hours, 24 hours and on discharge |
| Measure | Description | Time Frame |
|---|---|---|
| Post operative nausea and vomiting | 1 hour, 4 hours, 8 hours, 24 hours and on discharge |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jonathan K Randall, MRCS | Royal Berkshire NHS Foundation Trust | Principal Investigator |
| Simon B Middleton, FRCS | Royal Berkshire NHS Foundation Trust | Study Chair |
| Arnold Goede, MRCS | Royal Berkshire NHS Foundation Trust | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Royal Berkshire Hospital | Reading | Berkshire | RG1 5AN | United Kingdom |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| D010146 | Pain |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009461 | Neurologic Manifestations |
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| D012816 | Signs and Symptoms |