Effect of Methotrexate on the Relation Dose-effect of Infliximab in Ankylosing Spondylitis
Effect of Methotrexate on the Relation Dose-effect of Infliximab in Ankylosing Spondylitis
There is a great individual variability of pharmacokinetic of infliximab in patients treated for ankylosing spondylitis (AS). Moreover, some patients have a treatment with methotrexate (MTX), others have not.
Thus, the aim of this study is to assess the effect of MTX on the pharmacokinetic properties of infliximab in 30 patients treated for AS, 15 with MTX, 15 without.
Inclusion Criteria:
Exclusion Criteria: