Assessment of Myocardial Disease in Man Using Novel Non-invasive Diagnostic Tools

Assessment of Myocardial Disease in Man Using Novel Non-invasive Diagnostic Tools

This study will be testing two devices which are designed to detect cardiovascular disease in patients as early as possible. As there are now many therapies to prevent and treat this condition it is believed that detecting it early will help reduce the burden of the disease and permit more effective treatment.

The two devices the investigators are testing are the ViScope developed by HD Medical and a device developed by CSIRO. Both of these devices are simple, non-invasive and may provide useful information on how well the heart contracts and relaxes as well as valve function of the heart.

The investigators are planning to enroll 100 healthy subjects, 100 participants with risk factors for heart failure and 300 patients with varying types of heart failure.

The data collected from the experimental devices will be compared to the results from standard tests.

Patients will not have any of their therapies altered as part of this study.

Inclusion Criteria:

• Over 18 years
• Have provided consent

Risk factor patients also require:

• Hypertension > 2 years
• Diabetes > 2 years
• Known ischemia, TIA, or stroke
• Arrhythmia; or reduced renal function (eGFR<50 ml/min)

Heart Failure patients also require:

• LVEF <40%
• Receiving standard medication for the treatment of symptomatic systolic heart failure with an NYHA Class of II-IV.

Exclusion Criteria:

Health patients (must not have any of the following):

1. Cardiovascular disease
2. Receiving cardiovascular medication
3. Not in normal sinus rhythm (also required for HF patients)