Study Evaluating the Safety and Tolerability of SCA-136 in Healthy Japanese Male Subjects

An Ascending Multiple Dose Study of the Safety, Pharmacokinetics, and Pharmacodynamics of SCA-136 Administered Orally to Healthy Japanese Male Subjects

This study is being conducted to assess the safety and tolerability of ascending multiple oral doses of SCA-136 administered to healthy Japanese male subjects.

Inclusion criteria:

• Healty Japanese men willing to use a medically acceptable form of contraception.

Exclusion criteria:

• Any significant disease
• Positive urine drug screen
• Increased liver function tests
• Use of prescription drugs.