Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Joint Clinical Research Center | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Autism is considered as an invading disorder of the development. Asperger Syndrome (AS) is a particular form of autism and is difficult to diagnose. The Autism Spectrum Quotient (AQ) has been developed in order to measure the degree of autistic traits in autistic adolescent with normal intelligence (Baron-Cohen et al. 2001, 2006). AQ comprises 50 questions, with 5 groups of 10 questions assessing imagination, social skills, attention switching, attention to detail and communication skills. Each of these items scores 1 point if the respondent records abnormal or autistic like behaviour. The minimum score on the AQ is 0 and the maximum 50.
The principal objective of this study is to evaluate the accuracy of the French version of Autism Spectrum Quotient questionnaire.
Secondary objectives are to:
Evaluate if EQ and SQ can distinguish adolescents without psychiatric syndromes from those with classical autism or AS.
Evaluate if AQ, EQ and SQ can distinguish adolescents with psychiatric disorders from autistic adolescents.
Define the threshold of positivity for the 3 questionnaires.
4 groups of participants will be screened with the questionnaires: Group 1: 50 adolescents with AS or high functioning autism (HFS) diagnosed by psychiatrists using established criteria and with an IQ >85.
Group 2: 50 adolescents with AS or classical autism diagnosed by psychiatrists using established criteria 70\
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | 50 adolescents with AS or high functioning autism (HFS) diagnosed by psychiatrists using established criteria and with an IQ >85. |
| |
| 2 | 50 adolescents with AS or classical autism diagnosed by psychiatrists using established criteria 70\ |
| |
| 3 | 50 adolescents with psychiatric disorders but no autism syndrom. |
| |
| 4 | Sample of 50 healthy adolescents selected randomly from 200. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| questionnaires | Other | Primary outcome: Autism Spectrum Quotient (AQ) Secondary outcome measure: Empathy quotient (EQ) Systemizing quotient (SQ) WISC III or WISC IV ADOS score ADI score |
Inclusion Criteria:
Group 1 (AS/HFA) and 2 (AS/classic autism) :
Group 3 (adolescents with psychiatric disorders):
Group 4 (adolescent without psychiatric syndrome):
Exclusion Criteria:
For all groups :
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jean-Pierre Vignat, MDH | Contact | +33 4 37 90 11 75 | jpvignat@ch-st-jean-de-dieu-lyon.fr |
| Name | Affiliation | Role |
|---|---|---|
| Sabine Manificat, MDH | Centre Hospitalier Saint Jean de Dieu | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier Saint Jean de Dieu | Recruiting | Lyon | France |
Not provided
| ID | Term |
|---|---|
| D020817 | Asperger Syndrome |
| D001321 | Autistic Disorder |
| ID | Term |
|---|---|
| D000067877 | Autism Spectrum Disorder |
| D002659 | Child Development Disorders, Pervasive |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
Not provided
Not provided
| ID | Term |
|---|---|
| D011795 | Surveys and Questionnaires |
| ID | Term |
|---|---|
| D003625 | Data Collection |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D017531 | Health Care Evaluation Mechanisms |
Not provided
Not provided
Not provided
Not provided
Not provided
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |