To compare the effects of perceptual learning with patching on improving visual acuity and contrast sensitivity in payient with anisometropic amblyopia.

Patients with anisometropic amblyopia were randomized to patching or perceptual learning group. Corrected amblyopic logMAR visual acuity and contrast sensitivity function were measured at four-weekly intervals until visual acuity stabilized or amblyopia resolved. Improvement in visual acuity, contrast sensitivity, and the resolution of amblyopia were compared between groups.

Inclusion Criteria:

• Anisometropia without strabismus
• An interocular acuity difference of at least 0.2 logMAR in children (3-7 years of age) or in older children and adult patients without a history of patching or atropine penalization
• All patients wore their spectacle at least one year

Exclusion Criteria:

• A history of prior spectacle correction
• A history of patching or optical penalization
• The existence of an ocular disease that could contribute to decreased visual acuity
• Learning difficulties
• The presence of strabismus