Duodenal Jejunal Bypass for Type 2 Diabetes (DJBD)

Clinical Evaluation of the Effect of Duodenal Jejunal Bypass on Type Two Diabetes in Non Obese Adults

Study the effect of Duodenal jejunal bypass on human adults with type 2 diabetes.

Adults non obese ( BMI less than 34 ) will undergo duodenal jejunal bypass. The Outcome measures: Blood Sugar, Insulin,HbA1c, CCK,Gastrin, GIP1and 2, Ghrelin, Cholesterol, Triglycerides,FFA, C-Peptide.

Inclusion Criteria:

• Adults age 20-65
• Clinical diagnosis of type 2 diabetes
• Non obese with BMI less than 34.
• Oral agents or insulin to control T2DM.
• Inadequate control of diabetes as defined as HbA1c>/7.5
• Understanding of the mechanisms of action of the treatment

Exclusion Criteria:

• Children with type 1 diabetes
• Obese with BMI over 34
• Coagulopathy
• Liver cirrhosis
• Unable to comply with study requirements, follow-up or give valid consent
• Currently pregnant
• Previous upper abdominal surgery
• Inabilty to tolerate general anesthesia