study was not ethically acceptable to continue and therefore it was finally stopped

The purpose of this study is to compare the efficacy of quetiapine IR, following rapid titration versus conventional titration in patients with acute psychosis

Inclusion Criteria:

• provision of written informed consent
• male or female, aged 18-65 years
• requirement of hospitalization and in need for antipsychotic treatment for an acute psychotic episode
• able to swallow tablets from Day 1

Exclusion Criteria:

• In-patients who are anticipated to be discharged before evaluation of the primary outcome variable at Day 5
• patients with known relevant clinical disease
• history of syncope, or orthostatic hypotension
• patients with known neutropenia