| Secondary | Mean Percentage of Change in Glycosylated Hemoglobin (HbA1c) From Week 0(Baseline) to Week 16 Endpoint Least Squares Mean | Change in HbA1c from Week 0(baseline)to Week 16 endpoint least squares mean with 95% confidence intervals, change = week 16 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Least Squares Mean | 95% Confidence Interval | % change in HbA1c | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| | | Title | Denominators | Categories |
|---|
| | | Title | Measurements |
|---|
| - OG000-0.27(-0.52 to -0.02)
- OG001-0.58(-0.83 to -0.32)
- OG002-0.38(-0.64 to -0.13)
|
|
| |
| Secondary | Mean Percentage of Change in HbA1c From Week 0(Baseline) to Week 8 | change in HbA1c from Week 0(baseline) to week 8 mean and standard deviation change = week 8 - week 0. | | Posted | | Mean | Standard Deviation | % change in HbA1c | | 8 weeks change = week 8- week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Primary | Mean Percentage of Change in HbA1c From Week 0(Baseline) to Week 16 Endpoint | Change in HbA1c from Week 0(baseline) to Week 16 endpoint mean with standard deviation change = week 16 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Mean | Standard Deviation | % change HbA1c | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Change in Fasting Plasma Glucose (FPG) From Week 0(Baseline) to Week 8 Least Squares Mean | change in FPG from Week 0(baseline) to week 8 least squares mean and 95% confidence interval change = week 8 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Least Squares Mean | 95% Confidence Interval | mg/dL | | 8 weeks change = week 8- week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Change in FPG From Week 0(Baseline) to Week 16 Least Squares Mean | change in FPG from Week 0(baseline) to week 16 least squares mean and 95% confidence interval change = week 16 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Least Squares Mean | 95% Confidence Interval | mg/dL | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Mean Change in FPG From Week 0(Baseline) to Week 8 | mean change in FPG from Week 0(baseline) to Week 8 with standard deviation change = week 8 - week 0. | | Posted | | Mean | Standard Deviation | mg/dL | | 8 weeks change = week 8- week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Mean Change in FPG From Week 0(Baseline) to Week 16 | change in FPG from Week 0(baseline) to week 16 mean and standard deviation change = week 16 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Mean | Standard Deviation | mg/dL | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Change in Fasting Insulin From Week 0(Baseline) to Week 8 Least Squares Mean | change in fasting insulin from Week 0(baseline) to week 8 least squares mean and 95% confidence interval change = week 8 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Least Squares Mean | 95% Confidence Interval | uIU/mL | | 8 weeks change = week 8- week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Change in Fasting Insulin From Week 0(Baseline) to Week 16 Least Squares Mean | change in fasting insulin from Week 0(baseline) to week 16 least squares mean and 95% confidence interval change = week 16 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Least Squares Mean | 95% Confidence Interval | uIU/mL | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Mean Change in Fasting Insulin From Week 0(Baseline) to Week 8 | mean change in fasting insulin from Week 0(baseline) to week 8 with standard deviation change = week 8 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Mean | Standard Deviation | uIU/mL | | 8 weeks change = week 8- week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Mean Change in Fasting Insulin From Week 0(Baseline) to Week 16 | mean change in fasting insulin from Week 0(baseline) to week 16 with standard deviation change = week 16 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Mean | Standard Deviation | uIU/mL | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Change in Post-prandial Glucose From Week 0(Baseline) to Week 16 Least Squares Mean | change in post-prandial glucose from Week 0(baseline) to week 16 least squares mean with 95% confidence intervals change = week 16 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Least Squares Mean | 95% Confidence Interval | mg/dL | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Mean Change in Post-prandial Glucose From Week 0(Baseline) to Week 16 | mean change in post-prandial glucose from Week 0(baseline) to week 16 with standard deviation change = week 16 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Mean | Standard Deviation | mg/dL | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Mean Change in Post-prandial Insulin From Week 0(Baseline) to Week 16 | mean change in post-prandial insulin from Week 0(baseline) to week 16 with standard deviation change = week 16 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Mean | Standard Deviation | mg/dL | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Change in Low-Density Lipoprotein-C(LDL-C) From Week 0(Baseline) to Week 16 Least Squares Mean | change in LDL-C from Week 0(baseline) to week 16 least squares mean with 95% confidence intervals change = week 16 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Least Squares Mean | 95% Confidence Interval | mg/dL | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Mean Change in LDL-C From Week 0(Baseline) to Week 16 | mean change in LDL-C from Week 0(baseline) to week 16 with standard deviation change = week 16 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Mean | Standard Deviation | mg/dL | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Mean Percentage of Change in LDL-C Levels From Week 0(Baseline) to Week 16 | mean percent change in LDL-C levels from Week 0(baseline) to Week 16 mean with standard deviation change = week 16 - week 0. | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Mean | Standard Deviation | % change in LDL-C | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |
| Secondary | Mean Percentage of Change in LDL-C Levels From Week 0(Baseline) to Week 16 (Least Squares Mean) | percent change in LDL-C levels from Week 0(baseline) to Week 16 (least squares mean with 95% confidence interval) | The Full Analysis Set population included all randomized subjects who had taken at least 1 dose of study medication, and had a baseline and at least 1 post baseline HbA1c measurement. | Posted | | Least Squares Mean | 95% Confidence Interval | % change in LDL-C | | 16 weeks change = week 16 - week 0. | | | | ID | Title | Description |
|---|
| OG000 | Colesevelam | colesevelam tablets 625 mg | | OG001 | Rosiglitazone | rosiglitazone maleate 4mg | | OG002 | Sitagliptin | sitagliptin phosphate tablets 100mg |
| |