A Study of MK0359 in Patients With Chronic Asthma (0359-013)

A Multicenter, Randomized, Double-Blind, Crossover Study Comparing the Effect of MK0359 and Placebo in Adult Patients With Chronic Asthma

A study to test the effect of MK0359 in lessening the symptoms of asthma as compared to placebo.

Inclusion Criteria:

• You are between the ages of 18 and 45
• You have had a history for at least a year of COPD symptoms
• Your current asthma treatment is limited to short-acting beta-agonists(such as albuterol)
• You have a history of smoking one pack of cigarettes per day for 7 years
• You will not be away from home for more than 5 days during the study

Exclusion Criteria:

• You are unwilling to limit your alcohol use to less than 5 drinks per week
• You have been in a research study with an investigational drug or vaccine in the last 4 weeks
• You have donated blood in the last 4 weeks
• You have been hospitalized or had major surgery in the last 4 weeks
• You have been treated in the emergency room within the last 4 weeks or hospitalized within the last 3 months for your asthma
• You have a history of heart problems in the last 6 months
• You have a history of stomach problems
• You are unwilling to avoid grapefruit juice throughout the study