Ablation for ICD Intervention Reduction in Patients With CAD

Ablation for ICD Intervention Reduction in Patients With CAD - a Prospective Randomized Trial

The aim of this study is to assess the role of ablation in appropriate ICD interventions reduction in patients with coronary artery disease. The group will consist of 200 patients with implanted ICD and appropriate intervention in the 3 months prior to enrollment. The patients will be randomized into ablation arm and conventional treatment. Number of appropriate ICD interventions is the primary endpoint of this study. All patients will have control follow-up visits every 3 months. The follow-up will be based on ICD memory.

Inclusion Criteria:

• Coronary Artery Disease
• ICD implanted
• Appropriate ICD intervention during the 3 months prior to enrollment
• Coronary angiography during the 6 months prior to enrollment
• Possible revascularization
• Age over 18 years
• Signed informed consent

Exclusion Criteria:

• Age less then 18 years
• Pregnancy
• Active participation in other trial
• Heart failure (NYHA IV)
• Contraindications for ablation procedure: i.e. left ventricular thrombus, artificial aortic or mitral valve, no vascular access.
• Monomorphic, incessant, ventricular tachycardia
• Revascularization or other cardio-surgical procedure scheduled in the next 6 months