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To assess: a) The prevalence of Modic changes and other findings on lumbar magnetic resonance imaging (MRI), among Spanish adult chronic LBP patients, b) Patient characteristics and radiological findings associated with Modic changes.
Ten radiologists from six hospitals across six cities in Spain, consecutively recruited 487 adult patients (263 women and 224 men) in whom lumbar MRI had been prescribed for low back pain lasting ≥ 3 months. Patients' characteristics and imaging findings were assessed through previously validated instruments. A multivariate logistic regression model was developed to assess the features associated with Modic changes.
Outcome measures were: Gender, age, body mass index (BMI), life time smoking exposure, degree of physical activity, and image features (disk degeneration, type and extension of Modic changes, disk contour, annular tears, spinal stenosis and spondylolisthesis).
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| Measure | Description | Time Frame |
|---|---|---|
| Modic change | Modic change type, extension and volume | Upon assessment |
| Measure | Description | Time Frame |
|---|---|---|
| Patients' characteristics | Gender, age, body mass index (BMI), life time smoking exposure, and degree of physical activity | Upon assessment |
| Image features | Disk degeneration, type and extension of Modic changes, disk contour, annular tears, spinal stenosis and spondylolisthesis |
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Inclusion Criteria:
Exclusion Criteria:
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Patients seen for chronic low back pain at the hospitals of the Spanish National Health Service.
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| Name | Affiliation | Role |
|---|---|---|
| Francisco M Kovacs, MD, PhD | Kovacs Foundation, Palma de Mallorca, Spain | Study Director |
| Carlos Campillo, MD | IbSalut, Palma de Mallorca, Spain | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kovacs Foundation | Palma de Mallorca | Balearic Islands | 07012 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 3336678 | Background | Modic MT, Steinberg PM, Ross JS, Masaryk TJ, Carter JR. Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging. Radiology. 1988 Jan;166(1 Pt 1):193-9. doi: 10.1148/radiology.166.1.3336678. | |
| 8083266 | Background | Toyone T, Takahashi K, Kitahara H, Yamagata M, Murakami M, Moriya H. Vertebral bone-marrow changes in degenerative lumbar disc disease. An MRI study of 74 patients with low back pain. J Bone Joint Surg Br. 1994 Sep;76(5):757-64. |
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| ID | Term |
|---|---|
| D017116 | Low Back Pain |
| ID | Term |
|---|---|
| D001416 | Back Pain |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
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| Upon assessment |
| 11438138 | Background | Stirling A, Worthington T, Rafiq M, Lambert PA, Elliott TS. Association between sciatica and Propionibacterium acnes. Lancet. 2001 Jun 23;357(9273):2024-5. doi: 10.1016/S0140-6736(00)05109-6. No abstract available. |
| D013568 |
| Pathological Conditions, Signs and Symptoms |