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| Name | Class |
|---|---|
| Khon Kaen University | OTHER |
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To evaluate clinical and immunological outcome of children treated with HAART.
This is a long term cohort study that was started in 2002. Currently, there are 120 children enrolled in the study and are receiving HIV care according to standard practice set by the Thai Ministry of Public Health. HIV-infected parents also receive care at the same clinic.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Long-term pediatric cohort | Long-term follow-up cohort since 2003 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Zidovudine, Stavudine, Didanosine, Lamivudine | Drug | Refer to the Thai guideline for HIV management 2007 |
|
| Measure | Description | Time Frame |
|---|---|---|
| 1. To collect clinical and immunologic data of children treated with HAART 2. To collect clinical outcome data on children with HIV infection 3. To provide the best possible care to children with HIV infection | every 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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HIV-infected infants, children and adolescents (range age 1 day - 20 years old) who have participated in HIV-NAT trials
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| Name | Affiliation | Role |
|---|---|---|
| Kiat Ruxrungtham, MD, MSc | HIV-NAT, The Thai Red Cross AIDS Research Centre | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| HIV-NAT | Bangkok | 10330 | Thailand | |||
| Pediatric infectious diseases section, Chulalongkorn University |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Result | Bunupuradah T., Puthanakit T., Boonrak P., Butterworth O., Mengthaisong T., Intasan J., Ubolyam S., Kosalaraksa P., Engchanil C., Pancharoen C., Lumbiganond P., Phanuphak P., Ananworanich J., HIV-NAT Pediatric Study Team. Efficacy and safety of non nucleoside reverse transcriptase inhibitor (NNRTI) based highly active antiretroviral therapy (HAART) in Thai children with HIV, poster No. TUPEB128. Poster presented at the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention, Sydney, Australia, July 22-25, 2007 | ||
| 22026962 | Result | Bunupuradah T, Puthanakit T, Kosalaraksa P, Kerr S, Boonrak P, Prasitsuebsai W, Lumbiganon P, Mengthaisong T, Phasomsap C, Pancharoen C, Ruxrungtham K, Ananworanich J. Immunologic and virologic failure after first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children. AIDS Res Ther. 2011 Oct 26;8:40. doi: 10.1186/1742-6405-8-40. | |
| 24625136 |
| Label | URL |
|---|---|
| Click here for more information about HIV-NAT 015 | View source |
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| ID | Term |
|---|---|
| D015658 | HIV Infections |
| ID | Term |
|---|---|
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D015229 | Sexually Transmitted Diseases, Viral |
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| ID | Term |
|---|---|
| D015215 | Zidovudine |
| D018119 | Stavudine |
| D016049 | Didanosine |
| D019259 | Lamivudine |
| D019829 | Nevirapine |
| C098320 | efavirenz |
| D019258 | Saquinavir |
| D019469 | Indinavir |
| D019438 | Ritonavir |
| D019888 | Nelfinavir |
| ID | Term |
|---|---|
| D013936 | Thymidine |
| D011741 | Pyrimidine Nucleosides |
| D011743 | Pyrimidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
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PBMC
| Nevirapine, Efavirenz | Drug | Refer to the Thai guideline for HIV management 2007 |
|
| LPV/r, Saquinavir, Indinavir, Ritonavir, Nelfinavir | Drug | Refer to the Thai guideline for HIV management 2007 |
|
| Bangkok |
| 10330 |
| Thailand |
| Khon Kaen University | Khon Kaen | 40002 | Thailand |
| Result |
| Sirikum C, Sophonphan J, Chuanjaroen T, Lakonphon S, Srimuan A, Chusut P, Do TC, Prasitsuebsai W, Puthanakit T, Ananworanich J, Bunupuradah T; HIV-NAT 015 study team. HIV disclosure and its effect on treatment outcomes in perinatal HIV-infected Thai children. AIDS Care. 2014;26(9):1144-9. doi: 10.1080/09540121.2014.894614. Epub 2014 Mar 13. |
| D012749 | Sexually Transmitted Diseases |
| D016180 | Lentivirus Infections |
| D012192 | Retroviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |
| D006571 |
| Heterocyclic Compounds |
| D015224 | Dideoxynucleosides |
| D003853 | Deoxyribonucleosides |
| D009705 | Nucleosides |
| D009706 | Nucleic Acids, Nucleotides, and Nucleosides |
| D007288 | Inosine |
| D011684 | Purine Nucleosides |
| D011687 | Purines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D012263 | Ribonucleosides |
| D016047 | Zalcitabine |
| D003841 | Deoxycytidine |
| D003562 | Cytidine |
| D011725 | Pyridines |
| D007546 | Isoquinolines |
| D011804 | Quinolines |
| D013844 | Thiazoles |
| D013457 | Sulfur Compounds |
| D009930 | Organic Chemicals |
| D001393 | Azoles |