The objective of this study is to determine if twice-daily dosing of prednisolone (Pred Forte) is as effective as four-times-daily dosing of prednisolone for the prevention of retinal thickening and cystoid macular edema (CME) when either regimen is used concomitantly with twice-daily bromfenac.

Inclusion Criteria:

• · Male or female > 18 years of age scheduled to undergo cataract surgery

  • Must be in good general health. Patients with systemic diseases will be enrolled only if there are no ocular manifestations of their disease (ie diabetics with normal retinal exams)
  • Expected visual outcome of 20/25 or better.
  • Ability to provide informed consent and likely to complete all study visits

Exclusion Criteria:

• · Known contraindication to any study medication or any of their components

  • Uncontrolled systemic disease
  • Required use of ocular medications other than the study medications during the study
  • Abnormal pre-operative OCTs
  • Diabetic patients with a history of macular edema or diabetic retinopathy
  • AMD, epi-retinal membranes, retinal vein occlusion, or any pre-existing macular disease
  • Only one eye of each patient can be enrolled