Cone Beam CT Scanning in Lung and Bladder Cancer.

Improving the Accuracy of Radiotherapy Planning and Delivery Using Kilovoltage Cone Beam CT Imaging

To study changes in tumor and normal organ size and/or position which occur during a course of radiation treatments.

Inclusion Criteria:

• Patient has biopsy proven limited stage SCLC
• receiving radical concurrent chemoradiotherapy
• no prior chest RT
• no prior surgical resection of lung tumor
• no prior chemotherapy
• patients' lung tumors should be centrally-located to minimize the effect of respiratory motion
• patient has biopsy proven TCC bladder
• receiving radical concurrent chemoradiotherapy or RT alone
• no prior chemotherapy
• patient signs study-specific consent form

Exclusion Criteria:

• mixed small cell and non small cell histology
• patient not being treated with concurrent chemoradiotherapy
• chemoradiotherapy given sequentially
• previous chest RT
• previous chemotherapy
• prior surgical resection of lung mass
• patient ineligible for pelvic RT
• patient does not sign study consent