Capsaicin-Evoked Pain in Patients With CRPS

Capsaicin-Evoked Pain in Patients With Complex Regional Pain Syndrome

To evaluate the effect of capsaicin in patients with Complex Regional Pain Syndrome.

Primary outcome parameters: Capsaicin-induced pain and inflammation.

Secondary outcome parameters: Peripheral sensory and autonomic function.

Inclusion Criteria:

• Age: 18 or older.
• Pain in arm or hand > 3 months.
• Diagnosed with CRPS acc. to diagnostic research criteria (Harder et al., 2005)
• Inclusion of healthy subjects: age-, gender-, and BMI-matched.

Exclusion Criteria:

• Other significant disease affecting the parameters measured, including cardiovascular disease.
• Treatment with anticholinergics, sympathomimetics and parasympathomimetics, and alpha- and beta-adrenergics.