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Evaluation of the novel deep TMS H-Coil design as an augmentation measure in the treatment of medication resistant major depression. Stimulation is administered with and without cognitive-emotional provocation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Deep TMS stimulation | Experimental |
| |
| DTMS with positive cognitive-emotional provocation | Experimental |
| |
| DTMS with negative cognitive-emotional provocation | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transcranial Magnetic Stimulation (TMS) | Device |
|
| Measure | Description | Time Frame |
|---|---|---|
| HAMILTON RATING SCALE FOR DEPRESSION 24 items | 4 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Moshe Isserles, MD, MSc | Hadassah Medical Organization | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beer Yaacov Medical Center | Beer Yaacov | Israel | ||||
| Biological psychiatry unit, Psychiatric ward, Hadassah Medical organization |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20663568 | Background | Isserles M, Rosenberg O, Dannon P, Levkovitz Y, Kotler M, Deutsch F, Lerer B, Zangen A. Cognitive-emotional reactivation during deep transcranial magnetic stimulation over the prefrontal cortex of depressive patients affects antidepressant outcome. J Affect Disord. 2011 Feb;128(3):235-42. doi: 10.1016/j.jad.2010.06.038. Epub 2010 Jul 21. |
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| ID | Term |
|---|---|
| D003865 | Depressive Disorder, Major |
| ID | Term |
|---|---|
| D003866 | Depressive Disorder |
| D019964 | Mood Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D050781 | Transcranial Magnetic Stimulation |
| ID | Term |
|---|---|
| D055909 | Magnetic Field Therapy |
| D013812 | Therapeutics |
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| Jerusalem |
| Israel |