Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Unicity International | UNKNOWN |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This is a double-blind, placebo-controlled study to assess the effectiveness of BiosLife in lowering serum LDL cholesterol and raising HDL cholesterol. BiosLife is a natural supplement (mixed in water and taken twice daily) which contains guar gum and other natural soluble fibers, phytosterols, policosanol, and a proprietary chrysanthemum extract. Approximately 100 subjects with baseline LDL cholesterol of 110-190 mg/dL will be randomized in a 2:1 ratio to BiosLife or a look-alike placebo. Changes in lipids from baseline will be assessed at 6 weeks and 12 weeks.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| I | Active Comparator | Cohort I subjects will take supplement for 12 weeks |
|
| II | Placebo Comparator | Cohort II will take placebo for 12 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| BiosLife Complete | Dietary Supplement |
| ||
| Placebo |
| Measure | Description | Time Frame |
|---|---|---|
| LDL cholesterol | 12 weeks | |
| HDL cholesterol | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| triglycerides | 12 weeks | |
| LDL particle number | 12 weeks | |
| LDL particle size distribution |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Paul N Hopkins, MD, MSPH | University of Utah | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cardiovascular Genetics, University of Utah, 420 Chipeta Way, Room 1160 | Salt Lake City | Utah | 84108 | United States |
Not provided
| ID | Term |
|---|---|
| D006937 | Hypercholesterolemia |
| ID | Term |
|---|---|
| D006949 | Hyperlipidemias |
| D050171 | Dyslipidemias |
| D052439 | Lipid Metabolism Disorders |
| D008659 | Metabolic Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| 12 weeks |
| HDL particle number | 12 weeks |
| HDL particle size distribution | 12 weeks |
| VLDL particle number | 12 weeks |
| D009750 |
| Nutritional and Metabolic Diseases |