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The purpose of this study is to compared between conventional pterygium excision and AMT transplantation with suture and with fibrin glue.
There are few studies about use of fibrin glue in pterygium surgery with conjunctival auto-graft with promising outcome. Less recurrent rate, less discomfort and halve surgical time were reported.
Up to our knowledge,there is no report of fibrin glue in pterygium excision with amniotic membrane transplantation(AMT). There is conventional technique to use AMT in King Chulalongkorn Memorial Hospital because some benefits over conjunctival auto-graft e.g.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1Fibrin glue | Experimental | After pterygium excision, amniotic membrane was shaped and attached to bare scleral area using fibrin glue (Quixil®) |
|
| 2 Suture | Active Comparator | After pterygium excision, amniotic membrane was shaped and attached to bare scleral area using continuous suture with nylon 10-0 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Amniotic membrane transplantation using fibrin glue | Procedure | After pterygium excision, amniotic membrane was shaped and attached to bare scleral area using fibrin glue (Quixil®) in 16 eyes of 16 patients of FG group and continuous suture with nylon 10-0 in 16 eyes of 16 patients of SU group. |
| Measure | Description | Time Frame |
|---|---|---|
| Pain and discomfort during and after surgery using visual analog scale | during surgery and after surgery up to 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Surgical time | start and to the end of surgery | |
| Healing of epithelial defect on cornea and AMT | until 30 days | |
| Postoperative inflammation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ngamjit Kasetsuwan, MD | Ophthalmology Department, Faculty of Medicine, Chulalongkorn University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Ophthalmology, King Chulalongkorn Memorial hospital | Bangkok | 10330 | Thailand |
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| ID | Term |
|---|---|
| D011625 | Pterygium |
| ID | Term |
|---|---|
| D003229 | Conjunctival Diseases |
| D005128 | Eye Diseases |
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|
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| up to 30 days |
| Complications e.g. Recurrent, graft loss/dehiscent, re-operation | until last follow up |