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Open pilot study to collect information regarding the effect of atorvastatin on patients with active Crohns disease.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Atorvastatin | Drug |
| Measure | Description | Time Frame |
|---|---|---|
| Inflammatory markers in plasma before and after treatment. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in clinical activity index and mucosal inflammation after treatment. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Olof Grip, MD, PhD | Malmo University Hospital, Region Skåne | Principal Investigator |
| Anders Bredberg, MD, PhD | Malmo University Hospital, Region Skåne | Study Chair |
| Gunnel Bredberg, MD, PhD | Malmo University Hospital, Region Skåne | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Medicine, Division of Gastroenterology and Hepatology | Malmö | 20502 Malmö | Sweden |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19421322 | Derived | Grip O, Janciauskiene S. Atorvastatin reduces plasma levels of chemokine (CXCL10) in patients with Crohn's disease. PLoS One. 2009;4(5):e5263. doi: 10.1371/journal.pone.0005263. Epub 2009 May 6. |
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| ID | Term |
|---|---|
| D003424 | Crohn Disease |
| ID | Term |
|---|---|
| D015212 | Inflammatory Bowel Diseases |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| ID | Term |
|---|---|
| D000069059 | Atorvastatin |
| ID | Term |
|---|---|
| D011758 | Pyrroles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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| D007410 | Intestinal Diseases |
| D006538 |
| Heptanoic Acids |
| D005227 | Fatty Acids |
| D008055 | Lipids |