Endometrial Gene Expression Profile in Controlled Ovarian Stimulation Cycles With Premature Luteinization

Endometrial Gene Expression Profile in Controlled Ovarian Stimulation Cycles With Premature Luteinization

Previous studies have suggested that premature luteinization (PL)during controlled ovarian stimulation (COS) decreases the implantation rate due to a negative effect on the endometrium receptivity. This study aims to describe the impact on endometrial gene expression of PL in GnRH antagonist and GnRH agonist cycles.

Inclusion Criteria:

• Oocyte donors
• Age between 18-35 years old
• BMI 18-29
• NORMOGONADOTROPHICS
• PROGESTERONE ≥ 1.2 ng/ml on hCG day

Exclusion Criteria:

• PolyCystic Ovarian Syndrome (PCOS)
• Endometriosis