Nexium (Esomeprazole) in Symptom Adapted Therapy in GERD Patients

A Randomized, Open, Parallel-group Study to Evaluate the Efficacy of Three Different Patient Management Strategies During a 12 Weeks Maintenance Phase Following an Initial 4-weeks Acute Treatment Phase in Subjects With Symptoms Thought to be GERD Related

To compare the efficacy of three different long-term treatment strategies of reflux disease in primary care setting.

Inclusion Criteria:

• Subjects who seek medical advice in primary care for symptoms thought to be GERD related (GERD is a condition which develops when the reflux of stomach content causes troublesome symptoms and / or complications).

Exclusion Criteria:

• Subjects with any clinical GERD treatment (PPI, H2-receptor antagonists) within the last 3 months prior to Visit 1.
• A history of severe esophagitis or known other complications, with alarm symptoms