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The objective of this study is to evaluate the long-term safety and tolerability of ABT-089 in adults with ADHD.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ABT-089 | Drug | Open label study, subjects will take up to 80mg daily for 24 months. |
|
| Measure | Description | Time Frame |
|---|---|---|
| CAARS:INV | Day -1, Day 14, Months 1, 2, 3, 6, 9, 12, 15, 18, 21, 24 | |
| CGI-ADHD-S | Day -1, Day 14, Months 1, 2, 3, 6, 9, 12, 15, 18, 21, 24 |
| Measure | Description | Time Frame |
|---|---|---|
| AAQoL | Day -1, Months 3, 6, 9, 12, 15, 18, 21, 24 | |
| WPAI | Day -1, Months 3, 6, 9, 12, 15, 18, 21, 24 | |
| RUQ |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Laura Gault, MD, PhD, MD | AbbVie | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Site Reference ID/Investigator# 6109 | Mesa | Arizona | 85210 | United States | ||
| Site Reference ID/Investigator# 6765 |
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| Day -1, Months 3, 6, 9, 12, 15, 18, 21, 24 |
| FTND | Day -1, Months 1, 2, 3, 6, 9, 12, 15, 18, 21, 24 |
| Mesa |
| Arizona |
| 85210 |
| United States |
| Site Reference ID/Investigator# 6100 | Lafayette | California | 94549 | United States |
| Site Reference ID/Investigator# 6107 | San Diego | California | 92103-8620 | United States |
| Site Reference ID/Investigator# 6112 | Jacksonville | Florida | 32216 | United States |
| Site Reference ID/Investigator# 6096 | Maitland | Florida | 32751 | United States |
| Site Reference ID/Investigator# 6105 | Tampa | Florida | 33606 | United States |
| Site Reference ID/Investigator# 6094 | Smyrna | Georgia | 30080 | United States |
| Site Reference ID/Investigator# 6111 | Newton | Kansas | 67114 | United States |
| Site Reference ID/Investigator# 6113 | Farmington Hills | Michigan | 48336 | United States |
| Site Reference ID/Investigator# 6110 | Omaha | Nebraska | 68198 | United States |
| Site Reference ID/Investigator# 6099 | New York | New York | 10010 | United States |
| Site Reference ID/Investigator# 6106 | Chapel Hill | North Carolina | 27514 | United States |
| Site Reference ID/Investigator# 6102 | Portland | Oregon | 97210 | United States |
| Site Reference ID/Investigator# 6097 | Charleston | South Carolina | 29405 | United States |
| Site Reference ID/Investigator# 6098 | Memphis | Tennessee | 38119 | United States |
| Site Reference ID/Investigator# 6103 | Austin | Texas | 78704 | United States |
| Site Reference ID/Investigator# 6104 | Lake Jackson | Texas | 77566 | United States |
| Site Reference ID/Investigator# 6095 | Herndon | Virginia | 20170 | United States |
| Site Reference ID/Investigator# 6092 | Seattle | Washington | 98104 | United States |
| Site Reference ID/Investigator# 6101 | Middleton | Wisconsin | 53562 | United States |
| ID | Term |
|---|---|
| D001289 | Attention Deficit Disorder with Hyperactivity |
| ID | Term |
|---|---|
| D019958 | Attention Deficit and Disruptive Behavior Disorders |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| C108326 | pozanicline |
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