Study of MK-0476 in Adult Patients With Acute Asthma (0476-334)

MK-476 IV Formulation Phase III Open Label Exploratory Comparative Study - Acute Exacerbations of Asthma -

The study estimates the efficacy and safety of MK0476 and aminophylline intravenous administration in adult participants with acute asthma.

Inclusion Criteria:

• Adult participants with acute asthma attacks

Exclusion Criteria:

• Participant has any known or suspected, acute or chronic cause for their pulmonary symptoms other than asthma (e.g., COPD, chronic heart failure, etc.).
• Participant has a smoking habit (15 cigarettes per day) within a month prior to screening period, and/or has a smoking history (20 cigarettes per day) of more than 15 years.
• Participant has a disease of the cardiovascular, hepatic, renal, hematologic systems, or other severe disease.