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Evaluate the efficacy of Clobex® Spray as compared to Taclonex® Ointment in terms of Overall Disease Severity and Investigator Global Assessment.
Same as above.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Active Comparator | Clobex® Spray |
|
| 2 | Active Comparator | Taclonex® Ointment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Clobetasol Propionate, 0.05% | Drug | Topical, twice daily for 4 weeks |
|
| Measure | Description | Time Frame |
|---|---|---|
| Overall Disease Severity | End of treatment (Week 4) | |
| Tolerability assessments, incidence of adverse events | Baseline, Weeks 1, 2, 4 and 8 |
| Measure | Description | Time Frame |
|---|---|---|
| Overall Disease Severity | Weeks 1, 2 and 8 | |
| Investigator Global Assessment | End of treatment (week 4) and Weeks 1, 2 and 8 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ronald W Gottschalk, MD | Galderma Laboratories, LP | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Minnesota Clinical Study Center | Fridley | Minnesota | 55432 | United States | ||
| DermResearch, Inc. |
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| Calcipotriene and betamethasone dipropionate ointment | Drug | Topical, once daily |
|
|
| Austin |
| Texas |
| 78759 |
| United States |
| J & S Studies, Inc. | Bryan | Texas | 77802 | United States |
| Baylor Research Institute | Dallas | Texas | 75230 | United States |
| ID | Term |
|---|---|
| D002990 | Clobetasol |
| C055085 | calcipotriene |
| ID | Term |
|---|---|
| D001623 | Betamethasone |
| D013259 | Steroids, Fluorinated |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
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