Maintenance Therapy Using Lenalidomide in Myeloma | NCT00430365

ID	Type	Description	Link
2005-001554-24	EudraCT Number

Status Module

Name	Class
Intergroupe Francophone du Myelome	NETWORK
Celgene	INDUSTRY

Oversight Module

Design Module

Interventional Study Design

Biospecimen

No data available

No data is available for this block.

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
placebo group	Placebo Comparator	Administration of oral placebo	Drug: placebo
lenalidomide group	Experimental	Administration of lenalidomide	Drug: lenalidomide

Name	Type	Description	Arm Group Labels	Other Names
lenalidomide	Drug	oral drug	lenalidomide group	REVLIMID

Outcomes Module

Measure	Description	Time Frame
Determine the efficacy of Revlimid® at prolonging the duration of the post-transplant response.		2 years

Secondary Outcomes

Measure	Description	Time Frame
Assess the impact of Revlimid® on the post-transplant complete response rate		2 years
Compare survival without events and overall survival of patients in the lenalidomide arm with the control		2 years

Eligibility Module

Contacts/Locations Module

Name	Affiliation	Role
ATTAL Michel, Pr	University Hospital, Toulouse	Principal Investigator

Facility	Status	City	State	ZIP	Country	Contacts
ZNA Middelheim		Antwerp		2020	Belgium
Algemeen Centrumziekenhuis Antwerpen

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
9850028	Background	Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: an overview of 6,633 patients from 27 randomized trials. Myeloma Trialists' Collaborative Group. J Clin Oncol. 1998 Dec;16(12):3832-42. doi: 10.1200/JCO.1998.16.12.3832.
22571202	Result	Attal M, Lauwers-Cances V, Marit G, Caillot D, Moreau P, Facon T, Stoppa AM, Hulin C, Benboubker L, Garderet L, Decaux O, Leyvraz S, Vekemans MC, Voillat L, Michallet M, Pegourie B, Dumontet C, Roussel M, Leleu X, Mathiot C, Payen C, Avet-Loiseau H, Harousseau JL; IFM Investigators. Lenalidomide maintenance after stem-cell transplantation for multiple myeloma. N Engl J Med. 2012 May 10;366(19):1782-91. doi: 10.1056/NEJMoa1114138.

Derived Section

Miscellaneous Info Module

Submission Tracking

No data available

No data is available for this block.

Condition Browse Module

Intervention Browse Module

Ancestor Terms

ID	Term
D010797	Phthalimides
D010795	Phthalic Acids
D000146	Acids, Carbocyclic
D002264	Carboxylic Acids
D009930	Organic Chemicals
D010881	Piperidones
D010880	Piperidines
D006573	Heterocyclic Compounds, 1-Ring
D006571	Heterocyclic Compounds
D054833	Isoindoles
D006574	Heterocyclic Compounds, 2-Ring
D000072471	Heterocyclic Compounds, Fused-Ring

ID	Term
D009370	Neoplasms by Histologic Type
D009369	Neoplasms