Safety and Efficacy Study of Lithium in Bipolar Disorder

Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, Multicenter, Efficacy and Safety Study of Lithium in Bipolar I Disorder

The purpose of this study is to determine whether Lithium is safe and effective in the treatment of Bipolar I Disorder subjects with symptoms of acute mania.

Inclusion Criteria:

• Diagnosis of Bipolar 1 Disorder;
• Hospitalized or in the process of being hospitalized for a manic or mixed episode

Exclusion Criteria:

• History of rapid cycling;
• History of hypersensitivity or adverse reaction to lithium