The overall profile does not support development for obesity

To compare the effects of taranabant versus placebo on weight regain and weight maintenance after low calorie diet-induced weight loss in obese patients.

Inclusion Criteria:

• Patient has a body mass index (BMI) between 30 kg/m² and 43kg/m² and has maintained a stable weight (+/- 3kg) for at least 3 months prior to study start
• Patient is male or female >=18 and <= 65 years of age
• Patient understands the study procedures and alternative treatments available
• Patient is able to read, understand and complete study questionnaires

Exclusion Criteria:

• Patient has a history or presence of a major psychiatric disorder
• Patient has a recent history (within 6 months prior to signing the informed consent) diagnosis/episode/recurrence of stroke, TIA or neurological disorder
• Patient has a history of seizures or is at high risk of developing seizures
• Patient has systolic blood pressure >160mm Hg or diastolic blood pressure > 100 mm Hg
• Patient has diabetes mellitus as defined by medical history