The purpose of this research study is to compare subject comfort during and after injection with NADGL and Captique® Injectable Gel, in the nasolabial folds. Captique® is an FDA-approved product without lidocaine and is manufactured by Genzyme Biosurgery (Ridgefield, NJ). NADGL is a new product (not FDA approved) with lidocaine and is also manufactured by Genzyme Biosurgery. We do not know which of these treatments results in less pain during and after injection. The safety of NADGL is also being studied.

45 subjects are planned; a portion of these subjects will have skin of color

Inclusion Criteria:

• bilateral nasolabial folds with severity score of 3 or 4 on the 6 point scale.

Exclusion Criteria:

• pregnant/lactating women
• subjects who have an allergy to lidocaine or other amide-type anesthetics