Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment of Sever Acne

Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment

serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne

few studies has been done of serum levels Ca, P, PTH and vitamin D metabolites in patients receiving isotretinoin .In this study we measured serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne in 30 patients . the patients had no kown skeletal, endocrine ,renal and gastrointestinal disorders.

Inclusion Criteria:

• sever acne

Exclusion Criteria:

• renal disorders
• gastrointestinal disorders
• skeletal disorders
• endocrine disorders
• drugs such as glucocorticoids , thiazide diuretics, mineral multivitamins, anti acids, tetracyclines