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| Name | Class |
|---|---|
| Fresenius Medical Care North America | INDUSTRY |
This trial compares the efficacy of two artificial liver support systems, MARS (Molecular Adsorbents Recirculating System) and Prometheus (FPSA, Fractionated Plasma Separation and Adsorption), in removing albumin-bound substances such as bilirubin, bile acids, and cytokines.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MARS (Molecular Adsorbents Recirculating System) | Device | |||
| Prometheus (FPSA, Fractionated Plasma Separation and Adsorption) | Device |
| Measure | Description | Time Frame |
|---|---|---|
| serum levels of albumin-bound substances |
| Measure | Description | Time Frame |
|---|---|---|
| plasma clearance of albumin-bound substances |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Rudolf E. Stauber, MD | Medical University of Graz | Principal Investigator |
| Peter Krisper, MD | Medical University of Graz | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medical University of Graz | Graz | A-8036 | Austria |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16023249 | Result | Krisper P, Haditsch B, Stauber R, Jung A, Stadlbauer V, Trauner M, Holzer H, Schneditz D. In vivo quantification of liver dialysis: comparison of albumin dialysis and fractionated plasma separation. J Hepatol. 2005 Sep;43(3):451-7. doi: 10.1016/j.jhep.2005.02.038. | |
| 16847391 | Result | Jung A, Krisper P, Haditsch B, Stauber RE, Trauner M, Holzer H, Schneditz D. Bilirubin kinetic modeling for quantification of extracorporeal liver support. Blood Purif. 2006;24(4):413-22. doi: 10.1159/000094575. Epub 2006 Jul 14. |
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| ID | Term |
|---|---|
| D017093 | Liver Failure |
| D065290 | Acute-On-Chronic Liver Failure |
| ID | Term |
|---|---|
| D048550 | Hepatic Insufficiency |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
| D017114 | Liver Failure, Acute |
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