Transplantation of Autologous RPE Versus Translocation of Autologous RPE and Choroid in AMD

Transplantation of Autologous RPE Versus Translocation of Autologous RPE and Choroid in AMD

The purpose of this study is to evaluate two surgical interventions in patients with AMD.

The Submacular surgical trials have shown that submacular membrane extraction alone did not improve or preserve visual acuity in patients with AMD. Transplantation of autologous RPE and translocation of autologous RPE and choroid represent two promising therapeutic interventions in patients with AMD. This prospective, randomized clinical trial compares the two surgical treatments and additionally compares the clinical results (visual acuity, FLA) with OCT- and UHR-OCT data.

Inclusion Criteria:

• AMD and submacular cnv
• non responders to laser treatment or pdt
• treatment: rpe transplantation or rpe + choroid translocation
• age over 50 years

Exclusion Criteria:

• other additional retinal diseases, like diabetic or hypertensive retinopathy and vascular diseases.
• optic atrophy
• unstable glaucoma