The purpose of this study is to evaluate the efficacy of Optive versus Systane used concomitantly with topical cyclosporine for the treatment of dry eye.

Inclusion Criteria:

• · Males or females > 18 years old

  • Score of at least 2 and no more than 4 on the SESOD at the initial screening visit (mild to severe patients)
  • At least Grade 2 conjunctival staining
  • Likely to complete all study visits and able to provide informed consent

Exclusion Criteria:

• · Prior unsuccessful use of topical cyclosporine (defined as patients taking it at least 3 months and saw no improvements)

  • Current use of topical cyclosporine
  • Known contraindications to any study medication or ingredients
  • Female of child bearing potential not using reliable methods of birth control, or pregnant or lactating females.
  • Planned use of contact lenses (unless discontinued use ³ 30 days prior to randomization)
  • Active ocular diseases or uncontrolled systemic disease (blepharitis patients that are actively being treated or disease that is uncontrollable)
  • Ocular surgery within the past 3 months,
  • Active ocular allergies