The Effect of Viral Load on Intrahepatic Recurrence in Hepatitis B Virus (HBV)-Related Hepatocellular Carcinoma (HCC)

Prospective Cohort Study of the Effect of Serum HBV DNA Level on Intrahepatic Recurrence in Locally Treatable, HBV-related HCC Patients

The purpose of this study is to evaluate the effect of serum hepatitis B virus (HBV) DNA level on intrahepatic recurrence in locally treatable hepatocellular carcinomas (HCCs) related with HBV.

Prospective cohort study

Survival

• Overall survival rate
• Disease free survival rate

Recurrence

• Cumulative recurrence rate

Inclusion Criteria:

• Child-Pugh Class A or B
• Maximal tumor size less than 5 cm
• No previous history of treatment for hepatocellular carcinoma
• Recurrent hepatocellular carcinoma located more than 2 cm from the previous cancer site and is found more than 1 year's gap

Exclusion Criteria:

• Hepatocellular carcinoma in portal vein
• Hepatocellular carcinoma in hepatic vein