Gabapentin Treatment of Cannabis Dependence

Gabapentin for Cannabis Withdrawal and Use

This is a study to evaluate the efficacy of the medication gabapentin in treating persons with cannabis dependence.

This is a 12-week, double blind, placebo controlled, dose ranging study to evaluate the efficacy of gabapentin in treating outpatients with cannabis dependence. Counseling and research assessments occur weekly throughout the 12-week treatment phase.

Inclusion Criteria:

• Males or females age 18-65 with cannabis dependence
• Meets DSM-IV-TR criteria for Cannabis Dependence
• Smoked marijuana at least once a week in the 90 days prior to study participation
• Willing to attend 12 weekly study visits and 1 follow-up visit

Exclusion Criteria:

• Currently meets DSM-IV-TR criteria for dependence on illicit substances other than cannabis
• Significant medical disorders that will increase potential risk or interfere with study participation
• Women with childbearing potential who are pregnant, nursing, or refuse to use a reliable method of birth control
• Treatment with an investigational drug in the last month