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| ID | Type | Description | Link |
|---|---|---|---|
| AAAB2309 | Other Identifier | CUMC IRB |
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| Name | Class |
|---|---|
| Columbia University | OTHER |
| Dartmouth-Hitchcock Medical Center | OTHER |
| International Centre for Diarrhoeal Disease Research, Bangladesh | OTHER |
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The purpose of this study is to evaluate whether selenium and/or vitamin E are effective in preventing non-melanoma skin cancers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Experimental | Selenium |
|
| 2 | Experimental | Vitamin E |
|
| 3 | Experimental | Vitamin E + Selenium |
|
| Arm 4 | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Selenium | Dietary Supplement | 200 ug Selenium daily |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Skin Cancer | Incidence during the 6-year study period |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | Occurrence during the 6-year study period | |
| Diabetes | Incidence within 6-year study period |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Habibul Ahsan, MD | University of Chicago | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Columbia University Arsenic Research Project | Dhaka | Bangladesh | ||||
| ICDDR,B |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39851523 | Derived | Jasmine F, Almazan A, Khamkevych Y, Argos M, Shahriar M, Islam T, Shea CR, Ahsan H, Kibriya MG. Gene-Environment Interaction: Small Deletions (DELs) and Transcriptomic Profiles in Non-Melanoma Skin Cancer (NMSC) and Potential Implications for Therapy. Cells. 2025 Jan 10;14(2):95. doi: 10.3390/cells14020095. |
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| ID | Term |
|---|---|
| D012643 | Selenium |
| D014810 | Vitamin E |
| ID | Term |
|---|---|
| D018011 | Chalcogens |
| D004602 | Elements |
| D007287 | Inorganic Chemicals |
| D008903 | Minerals |
| D001578 |
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| vitamin E |
| Dietary Supplement |
100 mg Vitamin E daily |
|
| Dhaka |
| Bangladesh |
| Benzopyrans |
| D011714 | Pyrans |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |