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study of the value of the cytogenetics and the monitoring of the residual minimum disease in the standard treatment of acute myeloblastic leukemia.
The treatment scheme is purely welfare and therefore it does not require any approval of ethical committees for his application. It gathers the basic ideas of the present treatment of the AML, with optional induction according to preference of each center with daunorubicin or Idarubicin (x3) associated to AraC (x7). The patients who reach CR consolidate with an identical cycle to the used one in the induction. Later (if pte has identical donor HLA, and as much it as their doctors has preference by this option) receive allogenic transplant. The other patients who reach CR receive two intensifications, one that AraC to intermediate dose contains and another one with autologous transplant, previous preparation with Busulfán, Etoposide and AraC. Later all antileucemic treatment is suspended until possible relapse. This scheme of treatment is accompanied by a valuation of the quality of the CR with traditional morphology, Immunocytometry and molecular genetic study and of a pursuit of residual minimum disease (EMR) using the same techniques.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| chemotherapy | Drug |
Inclusion Criteria:
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AML of new diagnose, no treated previously
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| Name | Affiliation | Role |
|---|---|---|
| Diaz Mediavilla Joaquin, Dr | Hospital Clínico Universitario San Carlos | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital General de Alicante | Alicante | Alicante | Spain | |||
| Hospital Clínic |
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| Label | URL |
|---|---|
| Spanish association of Haematology | View source |
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| Barcelona |
| Barcelona |
| Spain |
| Hospital de la Santa Creu i Sant Pau | Barcelona | Barcelona | Spain |
| Hospital del Mar | Barcelona | Barcelona | Spain |
| Hospital Germans Trias i Pujol | Barcelona | Barcelona | Spain |
| Hospital vall d'Hebrón | Barcelona | Barcelona | Spain |
| Hospital Valle Hebrón-Materno Infantil | Barcelona | Barcelona | Spain |
| Xarxa assistencial de Manresa | Manresa | Barcelona | Spain |
| Hospital Universitario de Canarias | Santa Cruz de Tenerife | Canary Islands | Spain |
| Hospital Universitario Marqués de Valdecilla | Santander | Cantabria | Spain |
| Hospital general de Castellón | Castelló | Castellón | Spain |
| Hospital Puerta del Mar | Cadiz | Cádiz | Spain |
| Complejo Hospitalario Reina Sofía | Córdoba | Córdoba | Spain |
| Hospital Universitario Virgen de las Nieves | Granada | Granada | Spain |
| Hospital Virgen de las Nieves | Granada | Granada | Spain |
| Hospital Juan Canalejo | A Coruña | La Coruña | Spain |
| Complejo Hospitalario Universitario de Santiago | Santiago de Compostela | La Coruña | Spain |
| Fundación Jiménez Díaz | Madrid | Madrid | Spain |
| Hospital Clínico San Carlos de Madrid | Madrid | Madrid | Spain |
| Hospital Doce de Octubre | Madrid | Madrid | Spain |
| Hospital General Universitario Gregorio Marañón, Madrid | Madrid | Madrid | Spain |
| Hospital Universitario de la Princesa | Madrid | Madrid | Spain |
| Hospital General Universitario Morales Meseguer. | Murcia | Murcia | Spain |
| . Hospital Clínico Universitario Virgen de la Victoria | Málaga | Málaga | Spain |
| Clínica Universitaria de Navarra | Pamplona | Navarre | Spain |
| Hospital Central de Asturias | Oviedo | Oviedo | Spain |
| Hospital Son Dureta | Palma de Mallorca | Palma de Mallorca | Spain |
| Hospital Universitario Virgen del Rocío | Seville | Sevilla | Spain |
| Hospital Universitari de Tarragona Joan XXIII | Tarragona | Tarragona | Spain |
| Hospital Verge de la Cinta | Tortosa | Tarragona | Spain |
| Hospital Clínic | Valencia | Valencia | Spain |
| Hospital La Fe | Valencia | Valencia | Spain |
| Hospital Universitario Dr. Peset | Valencia | Valencia | Spain |
| Complejo Hospitalario Xeral-Cies | Vigo | Vigo | Spain |
| Hospital Clínico Lozano Blesa | Zaragoza | Zaragoza | Spain |
| Complejo Hospitalario de Cáceres | Cáceres | Spain |
| Area Hospitalaria Juan Ramón Jimenez | Huelva | Spain |
| Hospital general de Jerez de la Frontera | Jerez de la Frontera | Spain |
| Hospital Virgen Blanca de León | León | Spain |
| Hospital Clínico Universitario de Salamanca | Salamanca | Spain |
| Hospital General de Segovia | Segovia | Spain |
| Hospital Txagorritxu | Vitoria-Gasteiz | Spain |
| ID | Term |
|---|---|
| D015470 | Leukemia, Myeloid, Acute |
| ID | Term |
|---|---|
| D007951 | Leukemia, Myeloid |
| D007938 | Leukemia |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
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| ID | Term |
|---|---|
| D004358 | Drug Therapy |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
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