Drug Interaction Study of Famotidine and Atazanavir With Ritonavir in HIV-Infected Patients

Open-Label, Multiple-Dose, Drug Interaction Study to Assess the Effect of Famotidine With or Without Tenofovir on the Pharmacokinetics of Atazanavir When Given With Ritonavir in HIV-Infected Subjects

The purpose of this clinical research study is to assess the effect of Famotidine given twice daily on Atazanavir administered with Ritonavir in HIV-Infected subjects.

Inclusion Criteria:

• HIV-infected male and female subjects between the ages of 18 to 65 years old with a BMI 18 to 35 kg/m²
• Prior to enrollment subjects must be currently receiving Atazanavir/Ritonavir plus at least 2 NRTIs, must have plasma HIV RNA <400 copies/mL and have CD4 count >200 cells/mm³