Study to examine the concentration of the study drug, tigecycline, in human bone samples following the administration of multiple doses.

Inclusion:

• Men and nonlactating and nonpregnant women greater than or equal to 18 years of age.
• Healthy as determined by the investigator on the basis of medical history, physical examination, vital signs, and 12-lead electrocardiogram (ECG).
• Have a high probability for compliance with and completion of the study.

Exclusion:

• Subjects with chronic osteomyelitis.
• Subjects who have known or suspected hypersensitivity to tigecycline or other tetracyclines.
• Involvement in other investigational studies of any type within 30 days before test article administration.