Removal of Protein Bound Uremic Toxins by Modified Plasma Separation and Adsorption Combined With Hemodialysis

Removal of Protein Bound Uremic Toxins in Chronic Hemodialysis Patients by Modified Plasma Separation and Adsorption Combined With Hemodialysis

The aim of this study is to examine removal of protein bound uremic substances by mFPSA in chronic hemodialysis patients. mFPSA is an extracorporal blood purification system developed for detoxification in acute liver failure by removal of protein bound as well as water soluble substances.

Measurements of uremic protein bound substances before and after mFPSA and a preceding routine hemodialysis session.

Inclusion Criteria:

• Over the age of 18
• Anuria
• Chronic hemodialysis dependence

Exclusion Criteria:

• No present history of bleeding episodes
• Cardiac diseases