Long-Pulsed Dye Laser and Intense Pulsed Light for Skin Rejuvenation.

The purpose of the trial is to compare clinical efficacy and occurrence of side effects in the treatment of photodamaged skin with Pulsed Dye Laser and Intense Pulsed Light.

Inclusion Criteria:

• Mild to moderate bilateral facial photodamage
• Symmetry in the facial area of wrinkles, skin texture, pigmentary changes and telangiectasia
• Fitzpatrick's skin type of Type I, II, or III, without significant tan
• Age > 40 years
• Able to read and comprehend Danish
• Informed consent agreement signed by the subject
• Willingness to follow the treatment schedule and posttreatment follow-up evaluations
• Willingness to allow photographs of the treated area to be taken for evaluation of efficacy.

Exclusion Criteria:

• Scarring or infection of the area to be treated
• Known photosensitivity
• Presence of a suntan in the area to be treated
• Subjects taken medication known to induce photosensitivity in the previous three months
• Known anticoagulation or thromboembolic conditions
• Subjects taking anticoagulation medication
• Subjects taking Accutane within the past 6 months
• Subjects treated with aspirins or anti-inflammatory drugs
• Subjects who are immunocompromised or have a medical history that is inappropriate for the study per the investigator's clinical judgment.
• Dermabrasion, chemical peel, laser or IPL treatment, or collagen injection therapy in the facial area in the past 12 months.
• Previous formation of hypertrophic scars or keloids
• Subjects who are pregnant or lactating
• Asymmetry in the facial area of wrinkles, skin texture, pigmentary changes and telangiectasia