The main risk of aortic aneurysms is rupture that leads to a high risk of death. A preventive surgical treatment is thus needed. In order to reduce the morbidity and mortality associated with conventional surgery, an endovascular approach (insertion of an endovascular stent graft)is now widely favored. The main problem of this procedure is the occurrence of endoleaks (persistence of a communication between the aneurysm and the aorta). A new approach is proposed to prevent these endoleaks. The principle is to draw blood from the patient, separate the blood from the platelets, and reinject both platelet rich plasma (PRP) and autologous thrombin, in order to form a platelet gel (PRP + autologous thrombin). Before studying the efficacy of this technique, its safety of use and feasibility must be evaluated.

The main risk of aortic aneurysms is rupture. Onset is usually sudden, leading to the death of the patient in 80% to 90% of cases. The elective treatment of abdominal aortic aneurysms, therefore, seems to be a priority. In order to reduce the morbidity and mortality associated with conventional surgery, an endovascular approach (insertion of an endovascular stent graft using the endovascular aneurysm repair procedure) is now widely favored. The main problem, during follow-up of patients wearing an endovascular stent graft, is the occurrence of endoleaks resulting in retrograde filling of the aneurysm sac. The ideal is to prevent these endoleaks either by new developments in endovascular stent grafts or by using adjuvant therapy during the procedure. The principle is to draw blood from the patient, separate the blood from the platelets, and reinject it into two separate catheters, one with platelet rich plasma (PRP) and the other with autologous thrombin, in order to form a platelet gel (PRP + autologous thrombin). Before studying the efficacy of this technique, its safety of use and feasibility must be evaluated.

Inclusion Criteria:

Patient eligible to endovascular treatment:

• Any patient having an infrarenal or aortoiliac abdominal aortic aneurysm needing surgical treatment,
• With an infrarenal neck larger than 10 mm,
• No thrombi in the neck,
• Calcifications of the neck smaller than 30% of the circumference.
• The maximum diameter of the aneurysm must be at least 50 mm and/or an annual growth rate of more than 10 mm and/or if the aneurysm is symptomatic,
• With no major tortuosity of the two iliac axes with an aortoiliac angle greater than 80°,
• An external iliac diameter of at least 8 mm,
• An angle between the interrenal aorta and the neck of 0-45°.
• The patient must meet at least one of the operability criteria of the French Health Products Safety Agency (AFSSAPS)

Exclusion Criteria:

• Patient with a hemostatic disorder, previously known or discovered during the preoperative lab work-up,
• Patient whose arterial anatomy is incompatible with the criteria form use of a TALENT type endovascular stent graft,
• Patient with an aneurysm whose rapid progression (risk of rupture) does not allow a radiological and scanographic assessments to be performed,
• Patient allergic to the iodized contrast media,
• Disease of the connective tissue (Marfan's Syndrome) or inflammatory aneurysm,
• Patient with an aneurysm that includes the orifice of both internal iliacs,
• Patient in whom it is essential to keep the inferior mesenteric artery permeable,
• Patient surgically converted after failure of an endovascular technique,
• Pregnant women,
• Failure of stent graft insertion