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The World Health Organisation has warned that an influenza pandemic is inevitable. The avian influenza strain H5N1 is one of the leading candidates to cause the next influenza pandemic. Children are likely to be a special target group for vaccination; therefore, this study will test the safety and immunogenicity of an H5N1 pandemic influenza vaccine in healthy children.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| H5N1 pandemic influenza vaccine | Biological |
| Measure | Description | Time Frame |
|---|---|---|
| Safety and immunogenicity |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Terry M Nolan, Prof | Murdoch Childrens Research Institute | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Murdoch Childrens Research Institute | Melbourne | Victoria | 3052 | Australia | ||
| Princess Margaret Hospital for Children |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18801398 | Derived | Nolan T, Richmond PC, Formica NT, Hoschler K, Skeljo MV, Stoney T, McVernon J, Hartel G, Sawlwin DC, Bennet J, Ryan D, Basser RL, Zambon MC. Safety and immunogenicity of a prototype adjuvanted inactivated split-virus influenza A (H5N1) vaccine in infants and children. Vaccine. 2008 Nov 25;26(50):6383-91. doi: 10.1016/j.vaccine.2008.08.046. Epub 2008 Sep 16. |
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| ID | Term |
|---|---|
| D007251 | Influenza, Human |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D009976 | Orthomyxoviridae Infections |
| D012327 | RNA Virus Infections |
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| Perth |
| Western Australia |
| Australia |
| D014777 | Virus Diseases |
| D012140 | Respiratory Tract Diseases |