Oral Colchicine Combined With Intravitreal Infusion of Dexamethasone, LMW Heparin and 5-FU for Management of Proliferative Vitreoretinopathy (PVR)

To evaluate the efficacy of oral colchicine combined with intraoperative infusion of dexamethasone, low molecular weight heparin and 5-FU during vitrectomy for management of established proliferative vitreoretinopathy (PVR)

Inclusion Criteria:

• Cases with rhegmatogenous retinal detachment complicated by PVR grade C

Exclusion Criteria:

• History of pars plana vitrectomy for PVR grade C
• History of silicone oil injection
• History of ocular trauma
• Diabetic retinopathy
• Glaucoma
• Giant retinal tear