Glucose Control in Open Heart Surgery

Intensive Glucose Control Versus Conventional:Tendency Of Better Clinical Outcome In Open Heart Surgery

The purpose of the study is to seek if there is difference to state glucose level in 80-120mg/dl or 200mg/dl in patients submitted to open heart surgery

Hyperglycaemia in the intensive care unit and perioperative period has been accused to be one of the causes of worse clinical outcome. It is known that in open heart surgeries the glucose level must be set less than 200mg/dl, but new trials had set the glucose level lower than that: 140mg/dl in some studies and even lower (80-110mg/dl). Our trial had the intention to seek if there is difference setting glucose level in 2 different ones would modifies clinical outcome.

Inclusion Criteria:

• adult more than 21 years old
• open heart surgery with cardiopulmonary bypass

Exclusion Criteria:

• renal dysfunction
• reoperation
• use of inotropic support
• neurological dysfunction
• chronic pulmonary obstructive disease
• emergency or urgency