Effects of Amlodipine/Benazepril in the Hypertensive African-American Population With Type 2 Diabetes Mellitus

A Randomized, Multicenter, Study to Determine the Efficacy and Safety of Amlodipine/Benazepril Hydrochloride Versus Enalapril in the Treatment of Hypertension in an African-American Population With Type 2 Diabetes

This study evaluated the efficacy and safety of amlodipine/benazepril compared with that of enalapril in the treatment of hypertension in African-American patients with type 2 diabetes.

Inclusion Criteria:

• African-American
• males and females
• current diagnosis of type 2 diabetes documented by medical history;
• mean sitting diastolic blood pressure of ≥ 90 and ≤ 110 mm Hg;
• HbA1C ≤ 9.5%

Exclusion Criteria:

• having unilateral or bilateral renal artery stenosis;
• having clinically significant cardiac dysrhythmias;
• having a significant history of coronary artery disease within the past 6 months;
• having a history or diagnosis of congestive heart failure (CHF);
• having any clinically relevant cardiac valvular disease