Patients diagnosed with chronic sarcoidosis with fatigue for more than 6 months. Sarcoidosis and its treatment can greatly affect your quality of life. Many patients suffer from fatigue (feeling tired), lack of focus and concentration, in ability to organize their daily activities, and memory loss. These commonly reported symptoms often get in the way of everyday life.

This is to be a double blind, randomized trial with cross over of 12 patients with chronic sarcoidosis on stable systemic therapy. Patients will be screened for fatigue using a modified SNAP and Facit-F scores. Patients will be in the study for 20 weeks. Objective of study: To determine the effect of dexmethylphenidate hydrochloride, (d-MPH)(Focalin) on fatigue in Sarcoidosis. The is a common complaint in sarcoidosis, related to the chronic inflammatory nature of the disease. It may also related to therapy for the disease.

Inclusion Criteria:

• Diagnosis of sarcoidosis using standard criteria
• Disease for more than one year
• Complain of fatigue which has been present for more than six months.
• Over 18 years of age

Exclusion Criteria:

• Pregnancy
• Change in therapy for sarcoidosis in prior three months
• history of ventricular arrythmias
• Patients with a history of anxiety disorder, glaucoma, motor ties or a family history of Tourette's syndrome.
• Patients who are currently receiving or have received monoamine oxidase inhibitors within 14 days prior to study entry.