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The patient will be asked to participate in a research project designed to determine the best way to prevent bleeding and promote patient comfort after having kidney stones removed. Two standard methods for ending the surgery are being compared to a newer method. In one standard method, the patient will have a tube draining urine from the kidney after the procedure. This tube may also prevent bleeding from the kidney. In another standard method the patient will have a tube left internally that drains urine from the kidney to the bladder and a stitch will be used to close the incision and deeper tissues in the back. In the third potential option, a tube would be left internally to drain urine from the kidney to the patient's bladder and the surgical site would be filled with a clot promoting agent (FloSeal) which is a FDA approved agent specifically formulated to stop bleeding during surgical procedures.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Active Comparator | Floseal |
|
| 2 | Active Comparator | Cope-Loop/Nephrostomy Tube |
|
| 3 | Active Comparator | Fascial Stitch |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Floseal | Procedure | Bioglue that seals the kidney |
| |
| Cope Loop |
| Measure | Description | Time Frame |
|---|---|---|
| To determine which method of treatment causes the least pain to the patient. | one month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Michael K Louie, MD | UC Irvine, Department of Urology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of California, Irvine Medical Center-Department of Urology | Orange | California | 92868 | United States |
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| ID | Term |
|---|---|
| D007669 | Kidney Calculi |
| ID | Term |
|---|---|
| D053040 | Nephrolithiasis |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
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| ID | Term |
|---|---|
| C411004 | FloSeal Matrix |
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| Procedure |
Nephrostomy tube for fluid drainage from the kidney |
|
| Fascial Stitch | Procedure | Stitch that closes the kidney |
|
| D005261 |
| Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052878 | Urolithiasis |
| D014545 | Urinary Calculi |
| D052801 | Male Urogenital Diseases |
| D002137 | Calculi |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |