Contrast-enhanced ultrasound is supposed to improve the detection of myomas as well as improve the follow-up after specific treatments like embolization. It will also help the investigators better understand the mechanism of success or failure for embolization and could reduce the amount of particles injected by determining the endpoint of the procedure in order to treat the myomas while preserving the myometrium.

Before embolization of the uterine artery, 40 patients with unique or multiple myomas will be included prospectively in our study and evaluated with sonography before and after injection of Sonovue (2.4 ml) (Bracco Int Milano Italy). Pelvic ultrasound with contrast enhancement will be done the day after and six months after the procedure.

Microvascularization of the myomas and the endometrium will be described. Some tiny myomas which are not visible on conventional sonography could be identified for a perfect matching with MRI detection.

Inclusion Criteria:

• Uterine myomas with solid tissue (greater diameter lower than 15 cm)
• The embolization is planified during the 15 days after the contrast ultrasonography
• Written informed consent is signed

Exclusion Criteria:

• Intracavitary uterine mass possibly due to a polyp or endometrial cancer
• Necessity of using the endovaginal way of ultrasonography because of the myoma's size and accessibility
• Menopause
• Pregnancy and breastfeeding
• Recent cardiac affection
• History of acute cardiac disease

Women candidate for embolization of myomas