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| ID | Type | Description | Link |
|---|---|---|---|
| 5K02NS047099 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Neurological Disorders and Stroke (NINDS) | NIH |
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The purpose of this research study is to learn how people distribute their visual attention when looking at objects nearby versus far away, and why vision may become distracted at near versus far distances.
Visual distraction is a problem that more often occurs people who have suffered strokes than in the general population. Problems of visual attention generally appear immediately following a stroke, and may impair driving and other functions. While it is thought that there is a natural course of improvement over time, little is known about how this improvement occurs. Some studies suggest that recovery is only partial, meaning certain aspects of visual attention may improve while other aspects remain but escape notice.
The purpose of this study is to examine the effect of stroke on a person's visual attention when looking at objects nearby versus far away, and to learn why a person's visual attention may become more distracted at near versus far distances. The purpose of this study is also to understand how modeled interventions, such as eye patching or prism goggles, affect impairment measures of visual attention.
After an initial screening (including attention, thinking, memory, and visual judgment tests), participants will be given a neurological examination. Participants may be asked to perform visual tasks while wearing an eye patch or prism goggles. Next, they will be asked to perform a line bisection task by looking at lines on a video screen either at close or far distances and, using a laser pointer, marking the center of the lines as they appear on-screen. Participants may be asked to perform other, similar visual tasks as well.
Duration of the study for participants varies, ranging from 1 or 2 sessions totaling approximately 2 hours to multiple sessions spanning a year.
Research from this study may help researchers better understand problems associated with stroke and may lead to therapies designed to promote improved visual attention.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Persons who have had a stroke and either have, or do not have, a pathological asymmetry of perception, attention and action causing functional disability (spatial neglect; Barrett and Burkholder, 2006). | ||
| 2 | Healthy age- and education-matched volunteers |
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| Measure | Description | Time Frame |
|---|---|---|
| Kessler Foundation Neglect Assessment Process | a performance based and behavioral measure for spatial neglect that utilizes and standardizes the administration of the Catherine Bergego Scale (CBS) | From 1 or 2 sessions totaling approximately 2 hours to multiple sessions in one year |
| Measure | Description | Time Frame |
|---|---|---|
| Behavior Inattention Test Behavior Inattention Test | Conventional subtest, a set of paper and pencil test for spatial neglect | 2 weeks |
| Barthel Index | A functional independence assessment of daily tasks |
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Inclusion Criteria:
Exclusion Criteria:
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Persons who have had a stroke. Also, healthy volunteers.
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| Name | Affiliation | Role |
|---|---|---|
| A. M. Barrett, MD | Stroke Rehabilitation Research, Kessler Foundation Research Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kessler Foundation, 1199 Pleasant Valley Way | West Orange | New Jersey | 07052 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31999167 | Derived | Boukrina O, Chen P, Budinoska T, Barrett AM. Exploratory examination of lexical and neuroanatomic correlates of neglect dyslexia. Neuropsychology. 2020 May;34(4):404-419. doi: 10.1037/neu0000619. Epub 2020 Jan 30. | |
| 28167411 | Derived | Caulfield MD, Chen P, Barry MM, Barrett AM. Which perseverative behaviors are symptoms of spatial neglect? Brain Cogn. 2017 Apr;113:93-101. doi: 10.1016/j.bandc.2016.11.002. Epub 2017 Feb 3. |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| 2 weeks |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |